Immunotherapy for Lung Cancer

When other therapies are ineffective, immunotherapy may offer significant benefit to lung cancer patients. Immunotherapy uses materials made inside body or in a laboratory to boost the body’s natural defense system against tumor cells. The immunotherapy drugs, nivolumab (Opdivo) and pembrolizumab (Keytruda) are checkpoint inhibitors that target the PD-1 protein, which strengthens the immune response against the cancers. Atezolizumab (Tecentriq) is a drug that targets PD-L1, a protein related to PD-1 that is found on some tumor cells and immune cells. A better understanding of the role of immune checkpoints in the cancer immunity cycle and advancements in computational and bioinformatics platforms enabled the development of cancer neoantigen vaccination strategies.

 

  • Advances in Molecular Therapy
  • Immune Checkpoint Inhibition in Lung Cancer
  • CIMA vax

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