Genetic Abnormalities of Lung Cancer

Genetic mutations that are known to play critical roles in the development and progression of NSCLC include:

  • Epidermal growth factor receptor (EGFR) – the EGFR gene is responsible for a protein that helps a cell respond to its environment and can trigger cell growth, division, and survival.
  • KRAS – the KRAS gene is involved in regulating cell division.
  • Anaplastic lymphoma kinase (ALK) – the ALK gene provides instructions for a protein that plays an important role in cell growth, division, and maturation.

  • Epidermal Growth Factor Receptor (EGFR)
  • Kirsten RAS (KRAS)
  • Other Genetic Abnormalities in NSCLC
  • Anaplastic Lymphoma Kinase (ALK)

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